Correlative Light-Electron Microscopy (CLEM)
clem
Multi Modal Fusion
Photon
Forward-Model Signal Chain
Each primitive represents a physical operation in the measurement process. Arrows show signal flow left to right.
Spec Notation
(C → D) + (C → D) → ⊕
Benchmark Variants & Leaderboards
Correlative Light-Electron Microscopy (CLEM)
Correlative Light-Electron Microscopy (CLEM)
Spec Notation
(C → D) + (C → D) → ⊕
Standard Leaderboard (Top 10)
| # | Method | Score | PSNR (dB) | SSIM | Trust | Source |
|---|---|---|---|---|---|---|
| 🥇 | DiffusionCLEM | 0.881 | 39.1 | 0.958 | ✓ Certified | Chen 2024 |
| 🥈 | SwinCLEM | 0.847 | 37.5 | 0.944 | ✓ Certified | Huang 2023 |
| 🥉 | TransMorph | 0.819 | 36.2 | 0.931 | ✓ Certified | Chen 2022 |
| 4 | PINN-CLEM | 0.810 | 35.8 | 0.927 | ✓ Certified | Löffler 2023 |
| 5 | CLEM-Net | 0.781 | 34.5 | 0.912 | ✓ Certified | Spiers 2021 |
| 6 | VoxelMorph | 0.742 | 32.8 | 0.890 | ✓ Certified | Balakrishnan 2019 |
| 7 | CNN-Reg | 0.681 | 30.2 | 0.855 | ✓ Certified | de Vos 2019 |
| 8 | Landmark-Reg | 0.571 | 25.8 | 0.782 | ✓ Certified | Arganda-Carreras 2006 |
| 9 | Cross-Correlation | 0.512 | 23.5 | 0.741 | ✓ Certified | Thévenaz 1998 |
Mismatch Parameters (3) click to expand
| Name | Symbol | Description | Nominal | Perturbed |
|---|---|---|---|---|
| registration_error_(lm_to_em) | r_e | Registration error (LM to EM) (nm) | 0.0 | 100.0 |
| sample_deformation_(fixation) | s_d | Sample deformation (fixation) (shrinkage) | 0.0 | 1.0 |
| fluorescence_preservation | f_p | Fluorescence preservation (-) | 100.0 | 86.0 |